I mean is there any life beyond where we have gone so far? Like on any distant planet that hasn't been observed? (Technically, you could say that there is if you count any star, but is there any that won't kill us the instant we are several miles away)
And a better question is, why do people think we're irrelevant? sure, we're small compared to everything around us, but we're are closer to the bigger things in size than the smaller things